Expert advice about shingles vaccine in rheumatoid arthritis
Bruca Jancin writing in Rheumatology News reported on a lecture given by Dr. John Cush at the Winter Rheumatology Symposium. While the recommendation is against giving zoster vaccine to patients on biologics, Dr. Cush did a survey of more than 200 patients inadvertently given the vaccine while on biologics. Not one case of shingles occurred. A study conducted in Alabama of 633 patients on biologics given inadvertent zoster vaccine also failed to show an increase in shingles risk and actually showed a 39% reduction in shingles risk.
Comment: Reassuring news that shingles vaccine, even though it is live, is not the end of the world if given to patients on biologic therapy. That being said, I still think that a 4 week waiting period before vaccination while holding a biologic is prudent.
Janis Kelly writing in Medscape reported the natural history of rheumatoid arthritis (RA) has changed dramatically since 1990, apparently as a result of advances in RA treatment, such as the use of biologicals and more aggressive “treat to target” clinical approaches. The annual progression rates in studies of long-term progression reported after 1990 were less than half those reported in the prior 25 years, researchers report in an article published in the journal, Rheumatology.
Comment: When I talk with my patients with rheumatoid arthritis I tell them it’s actually a good diagnosis to have since the likelihood of going into remission is quite high.
Sometimes new uses for old drugs are found. This is particularly true when you go across medical disciplines as the next item will show…
Rheumatoid arthritis drug may help treat ovarian cancer
Dr. Victor Marchione, writing in Bel Marra Health reported an older rheumatoid arthritis drug may help treat ovarian cancer.
Rheumatoid arthritis is an autoimmune disorder and many autoimmune disorders share links with certain forms of cancer. Because of these shared links cancer treatment drugs can sometimes benefit certain autoimmune disorders and vice versa. Such is the case with a drug known as auranofin.
Auranofin is commonly used in the treatment in rheumatoid arthritis, but a new study suggests it may aid in the treatment of ovarian.
Some patients with ovarian cancer have a mutation in the BRCA1 gene. In the study, the researchers found that those patients responded well to the rheumatoid arthritis drug.
Comment: auranofin is oral gold… an old old drug that really never panned out. But this news is certainly promising.
Not all the news about non-steroidal drugs is bad. In fact, this next item might surprise you…
Decreased Risk of Dementia With Prolonged NSAID Exposure in RA
Lauren Grygotis writing in Neurology Advisor reported a longer period of treatment with non-steroid anti-inflammatory drugs (NSAIDs) was associated with a decreased risk of dementia among patients with rheumatoid arthritis (RA) in a large population-based cohort, according to recent findings published in Medicine.
Previous studies have suggested that early inflammation, cardiovascular disease, and depression are associated with increased risk of dementia. The authors of the study noted that NSAIDs are “commonly used for treating RA, and several studies suggest that NSAIDs reduce the risk of Alzheimer’s disease or dementia in patients with RA.”
Have you ever wondered if there are natural ingredients that would help as well as pharmaceuticals? Many doctors don’t agree but the latest science suggests they might be wrong… next
Green Tea May Help Ease Rheumatoid Arthritis Symptoms
Ashley Boynes-Shuck writing in Healthline reported a new study appearing in the medical journal, Arthritis and Rheumatology, shows that a compound found in green tea may hold promise in rheumatoid arthritis (RA) disease management.
Herbal teas have been in use to treat various ailments for literally thousands of years, with estimates of its medicinal use since before the beginning of recorded history.
Green tea has been touted by health coaches, nutritionists, doctors, and dietitians for decades. The drink is particularly known for anti-oxidant properties.
Now, green tea is being heralded as way to reduce inflammation in the body as well. In fact, the recent study concludes the drink has potentially as a regularly prescribed treatment for patients with RA, although so far it has only been tested on mice.