Browsing Tag: Obesity

Americans More Obese


This next item falls into the , “Duh…. No kidding” category…

Americans heavier than they were two decades years ago, report says

Alexandra Sifferlin writing in Time reported the CDC’s National Center for Health Statistics found that US men and women “weigh about 15 pounds more than they did 20 years ago.” According to the report, the average 5’9” man now weighs 195.7 pounds and the average 5’4” woman weighs 168.5 pounds. Time noted “men and women’s heights were about the same two decades ago.” The study also found that average 11-year-old boys and girls now weigh about 13 and 7 pounds more, respectively, in comparison to 1988-94. Boys have grown about an inch on average since then, while girls this age have remained the same height.

Comment: Overseas, Americans are referred to as the Porkus Americanus species.

Fat Stem Cells for Knee Arthritis


More good news on the stem cell front… next

New Treatment Shows Promise for Crippling Knee Arthritis

Alan Mozes writing for Healthday reported on a small study that demonstrated that just one injection of stem cells can reduce pain and inflammation.

The idea is experimental: Extract stem cells from a patient’s own body fat — cells known for their ability to differentiate and perform any number of regenerative functions — and inject them directly into the damaged knee joint.

To explore the potential of stem cell therapy, the study authors focused on 18 French and German men and women, aged 50 to 75, all of whom had struggled with severe knee osteoarthritis for at least a year before joining the study.

Between April 2012 and December 2013, all of the patients first underwent liposuction to extract fat-derived samples of a specific type of stem cell. The researchers noted that these particular stem cells have been shown to have immune-boosting and anti-scarring properties, as well as the ability to protect against cell “stress” and death.

A third of the patients received a single “low-dose” injection of their own stem cells directly into their knee. Another third received a “medium-dose” injection, involving a little more than four times the amount of stem cells, while the remaining group received a “high-dose” injection packed with roughly five times as many stem cells as the medium-dose group.

After six months, the study team found that all three groups showed improvements in terms of pain, function and mobility.

However, only those in the low-dose group were determined to have “statistically significant” improvements in terms of both knee pain and function recovery.

Comment: this data is in keeping with other studies.

Obesity Reduces Remission Rates in Rheumatoid Arthritis


A huge barrier to obtaining remission in rheumatoid arthritis… pun intended

Obesity Halves Chance for RA Remission, Study Suggests

Janis Kelly writing in Medscape reported rheumatoid arthritis (RA) remission rates were significantly lower among patients who were obese compared with nonobese patients, according to a systematic review and meta-analysis reported in an article in Arthritis Care & Research. The authors also found that disease activity scores were significantly higher and call for studies to determine whether interventions to reduce body mass index (BMI) might also improve outcomes in RA.

Coauthor Gilaad G. Kaplan, MD, MPH, told Medscape Medical News, “Obesity is a growing problem for society. Our work adds another negative stigma to the obesity epidemic…[O]bese patients who are diagnosed with [RA] are more likely to fare worse than nonobese individuals with [RA]. Because obesity is a modifiable risk factor, future studies are needed to determine whether adding weight loss to a treatment plan will improve outcomes for these patients.”

Comment: Obesity is a growing epidemic.  We need to inform patients with rheumatoid arthritis that they need to lose weight.

 

Body Weight Influence on Response to RA Treatment

Does weight have influence on the rate of  remission in RA?

Weight Could Influence Rheumatoid Arthritis Relief

Alex Kramer writing for Healthday reported people with rheumatoid arthritis may be more likely to achieve remission if they maintain a healthy body weight, according to new research.

The study found that those who were heaviest had almost 65 percent reduced odds of disease remission. Being underweight also lowered the odds of remission.

“Medication for rheumatoid arthritis is not as effective on the overweight population,” said Dr. Susan Goodman, the study’s lead author and a rheumatologist at the Hospital for Special Surgery in New York City.

Comment: Another mark against obesity.

Rheumatoid Arthritis Obesity


What’s weight got to do with RA? More than you think… next

Weight Could Influence Rheumatoid Arthritis Relief

Alex Kramer writing for Healthday reported people with rheumatoid arthritis may be more likely to achieve remission if they maintain a healthy body weight, according to new research.

The study found that those who were heaviest had almost 65 percent reduced odds of disease remission. Being underweight also lowered the odds of remission.

“Medication for rheumatoid arthritis is not as effective on the overweight population,” said Dr. Susan Goodman, the study’s lead author and a rheumatologist at the Hospital for Special Surgery in New York City.

Findings from the new research were presented earlier this month at the American College of Rheumatology annual meeting in Boston.

Comment: Fat cells produce adipokines, proteins that aggravate inflammation.

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