A commonly used medication for heart disease may have another use… next
Statins May Reduce Alzheimer’s Risk, Study Suggests
Muir reporting for ABC World News Tonight stated, “A new study shows that high use of…statins” may be associated with “a lower risk of Alzheimer’s for patients over the age of 65.” The study was published in JAMA Neurology.
Comment: It’s interesting how drugs for one disease may help another.
Arthritis drug could reduce risk of having Alzheimer’s disease
Nicholas Bakalar writing for Business Standard reported a drug used to treat rheumatoid arthritis may have benefits against Alzheimer’s disease, researchers report.
Rheumatoid arthritis is an autoimmune disease believed to be driven in part by tumour necrosis factor, or TNF, a protein that promotes inflammation. Drugs that block TNF, including an injectable drug called etanercept, have been used to treat rheumatoid arthritis for many years.
TNF is also elevated in the cerebrospinal fluid of Alzheimer’s patients.
Researchers identified 41,109 men and women with a diagnosis of rheumatoid arthritis and 325 with both rheumatoid arthritis and Alzheimer’s disease. In people over 65, the prevalence of Alzheimer’s disease was more than twice as high in people with rheumatoid arthritis, as in those without it. The study is in CNS Drugs.
But unlike patients treated with five other rheumatoid arthritis drugs, those who had been treated with etanercept showed a significantly reduced risk for Alzheimer’s disease.
Comment: Interesting to see what future developments occur.
Not all the news about non-steroidal drugs is bad. In fact, this next item might surprise you…
Decreased Risk of Dementia With Prolonged NSAID Exposure in RA
Lauren Grygotis writing in Neurology Advisor reported a longer period of treatment with non-steroid anti-inflammatory drugs (NSAIDs) was associated with a decreased risk of dementia among patients with rheumatoid arthritis (RA) in a large population-based cohort, according to recent findings published in Medicine.
Previous studies have suggested that early inflammation, cardiovascular disease, and depression are associated with increased risk of dementia. The authors of the study noted that NSAIDs are “commonly used for treating RA, and several studies suggest that NSAIDs reduce the risk of Alzheimer’s disease or dementia in patients with RA.”
Is there a relationship between rheumatoid arthritis and Alzheimer’s disease. The answer next…
Rheumatoid arthritis patients may also have increased risk for Alzheimer’s disease
Reported in Healio, Researchers from the Cleveland Clinic found patients with rheumatoid arthritis may have an increased risk of developing Alzheimer’s disease and other shared risk factors, according to a presentation at the American College of Rheumatology meeting. “These are two very common diseases, and perhaps the inflammatory burden may provide important clues to the pathogenesis of Alzheimer’s disease,” study author, M. Elaine Husni, MD, MPH, a rheumatologist and director of the Arthritis & Musculoskeletal Treatment Center at the Cleveland Clinic was quoted as saying.
Well… if you have gout, look on the bright side…next…
Gout May Protect Against Alzheimer’s Disease
Kate Johnson writing for MedPage Today reported new research suggests that patients diagnosed with gout face a lower risk of developing Alzheimer’s disease (AD) compared with people without gout.
“Our findings provide the first population-based evidence for the potential protective effect of gout on the risk of AD, and support the neuroprotective role of uric acid,” said Hyon Choi, MD, the study’s senior investigator, and director of epidemiology at Massachusetts General Hospital.
Comment: Well then… maybe the pain is worth putting up with…