Thread Carpal Tunnel Release – A Women’s Perspective

Here’s a brief animation on the Thread Carpal Tunnel Release.

A simple RA drug that can cut down the risk of heart attacks and strokes… next

First-Line RA Drug Linked to Decreased CVD Risk

Kate Johnson writing for Medpage Today reported the antimalaria drug hydroxychloroquine (Plaquenil) that is used as first-line therapy in patients with rheumatoid arthritis (RA) is also associated with reduced cardiovascular risk, especially at higher doses, a new study shows.
“This is the first study to answer this question specifically,” said Michael Shapiro, MD, from the Sackler Faculty of Medicine\ at Tel Aviv University in Israel, who suggested a “protective effect” of the drug.

The retrospective analysis included 514 RA patients ages 18 years or older who were treated at a single institution between 2003 and 2013.

Comment: I use Plaquenil sparingly for patients with mild RA. Nonetheless this study shows that even a mild drug can have beneficial effects.

Rheumatoid Arthritis: TNF Inhibitors Linked to Less Fatigue

Lara Pullen writing for Medscape reported on a study demonstrating patients with rheumatoid arthritis (RA) report substantial improvement of fatigue after beginning anti–tumor necrosis factor α (TNF-α) therapy. In particular, employed women with a low level of disability were the most likely to experience an improvement in fatigue. Pain, however, was not a significant predictor of improvement.

Although fatigue is generally considered a significant factor in RA, it is rarely a primary endpoint in clinical trials. Katie L. Duce, a PhD student from the Epidemiology Group, Institute of Applied Health Sciences, University of Aberdeen, United Kingdom, and colleagues published the results of their long-term observational cohort study in the journal, Rheumatology.
Comment: Second only to pain and stiffness, fatigue is a major problem for patients with RA. In my experience, TNF inhibitors are great at reducing fatigue.

A big risk for those with ankylosing spondylitis

Study Links Ankylosing Spondylitis and CVD

Kate Johnson writing for Medpage Today reported Canadian researchers have shown for the first time that patients with ankylosing spondylitis (AS) face an increased risk of death from cardiovascular and cerebrovascular disease.

“This is the first population-based study to demonstrate that spondyloarthritis is associated with significant risk of vascular mortality,” said study investigator Nisha Nigel Haroon, from the University of Toronto, in Ontario. “A comprehensive strategy is needed to screen and treat vascular risk factors in patients with AS.”

Comment: This risk is similar to that for rheumatoid arthritis and psoriatic arthritis.

Well… if you have gout, look on the bright side…next…

Gout May Protect Against Alzheimer’s Disease

Kate Johnson writing for MedPage Today reported new research suggests that patients diagnosed with gout face a lower risk of developing Alzheimer’s disease (AD) compared with people without gout.

“Our findings provide the first population-based evidence for the potential protective effect of gout on the risk of AD, and support the neuroprotective role of uric acid,” said Hyon Choi, MD, the study’s senior investigator, and director of epidemiology at Massachusetts General Hospital.

Comment: Well then… maybe the pain is worth putting up with…

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