Estrogen-Only Hormone Therapy May Benefit Older Women With Joint Pain

Lynda Williams writing in Medwire reported, “Postmenopausal women with joint pain may benefit from taking estrogen-only hormone therapy,” according to research published in Menopause. Investigators looked at data from the Women’s Health Initiative. The researchers found that “women randomly assigned to receive daily oral conjugated equine estrogen (0.625 mg/day) after hysterectomy were significantly less likely to experience joint pain at 1 year than women given placebo.” The investigators found that “estrogen treatment was also associated with a significant reduction in mean joint pain severity scores at 1 year and both benefits persisted for up to 3 years of follow-up.”

Comment: Whether this will balance out the other risks of estrogen is still not known.


Nancy Walsh writing in MedPage Today reported, “Highly obese patients can derive similar benefits from total knee replacement surgery as other patients,” according to a study presented at the annual meeting of the American Academy of Orthopaedic Surgeons. “During nine years of follow-up, highly obese individuals with a body mass index of at least 35 kg/m2 showed an increase of 50 points on Knee Society knee function scores, compared with an increase of 52 and 56 points for mildly obese and nonobese individuals, respectively,” the study found.

Comment: Not what I would have expected… that’s for sure. Still not a license to chow down at the all you can eat buffet.

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